Synthesis of Indolo[2,3-c]quinolin-6(7H)-ones and Antimalarial Isoneocryptolepine. Computational Study on the Pd-Catalyzed Intramolecular C

Synthesis of Indolo[2,3-c]quinolin-6(7H)-ones and Antimalarial Isoneocryptolepine. Computational Study on the Pd-Catalyzed Intramolecular C–H Arylation

Published:2020-11-30 Issue:1 Volume:86 Page:128-145
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Szabó Tímea¹^ORCID,Papp Marcell¹²^ORCID,Németh Dóra Rita¹,Dancsó András¹^ORCID,Volk Balázs¹^ORCID,Milen Mátyás¹^ORCID

Affiliation:

1. Directorate of Drug Substance Development, Egis Pharmaceuticals PLC, P.O. Box 100, H-1475 Budapest, Hungary

2. Department of Inorganic and Analytical Chemistry, Budapest University of Technology and Economics, Szent Gellért tér 4, H-1111 Budapest, Hungary

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.0c01832

Reference53 articles.

1. Indoloquinolines as Scaffolds for Drug Discovery

2. Synthesis and biological evaluation of indoloquinoline alkaloid cryptolepine and its bromo-derivative as dual cholinesterase inhibitors

3. Methods of synthesis of natural indoloquinolines isolated from Cryptolepis sanguinolenta

4. Die Konstitution des Alkaloids Cryptolepin

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