Double Click: Unexpected 1:2 Stoichiometry in a Norbornene–Tetrazine Reaction-Reference-Cited by-同舟云学术

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Double Click: Unexpected 1:2 Stoichiometry in a Norbornene–Tetrazine Reaction

Published:2023-04-14 Issue:9 Volume:88 Page:5341-5347
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Devi Gitali¹^ORCID,Hedger Adam K.¹²^ORCID,Whitby Richard J.³^ORCID,Watts Jonathan K.¹²⁴^ORCID

Affiliation:

1. RNA Therapeutics Institute, UMass Chan Medical School, Worcester, Massachusetts 01605, United States

2. Department of Biochemistry and Molecular Biotechnology, UMass Chan Medical School, Worcester, Massachusetts 01605, United States

3. Department of Chemistry, University of Southampton, SO17 1BJ Southampton, U.K.

4. Li Weibo Rare Disease Institute, UMass Chan Medical School, Worcester, Massachusetts 01605, United States

Funder

National Center for Advancing Translational Sciences

National Institute of Neurological Disorders and Stroke

Ono Pharmaceutical

Pharmaceutical Research and Manufacturers of America Foundation

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.2c02861

Reference28 articles.

1. Inverse electron demand Diels–Alder reactions in chemical biology

2. Inverse electron demand Diels–Alder (iEDDA)-initiated conjugation: a (high) potential click chemistry scheme

3. Bioorthogonal Tetrazine-Mediated Transfer Reactions Facilitate Reaction Turnover in Nucleic Acid-Templated Detection of MicroRNA

4. A Bioorthogonal Near-Infrared Fluorogenic Probe for mRNA Detection

5. Tetrazine-Based Cycloadditions: Application to Pretargeted Live Cell Imaging

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