Discovery of a Potent α-Galactosidase Inhibitor by in Situ Analysis of a Library of Pyrrolizidine–(Thio)urea Hybrid Molecules Generated via Click Chemistry-Reference-Cited by-同舟云学术

Discovery of a Potent α-Galactosidase Inhibitor by in Situ Analysis of a Library of Pyrrolizidine–(Thio)urea Hybrid Molecules Generated via Click Chemistry

Published:2018-07-17 Issue:16 Volume:83 Page:8863-8873
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Elías-Rodríguez Pilar¹,Pingitore Valeria¹,Carmona Ana T.¹^ORCID,Moreno-Vargas Antonio J.¹^ORCID,Ide Daisuke²,Miyawaki Shota²,Kato Atsushi²,Álvarez Eleuterio³^ORCID,Robina Inmaculada¹^ORCID

Affiliation:

1. Department of Organic Chemistry, Faculty of Chemistry, University of Seville, C/Prof. García González, 1, 41012 Seville, Spain

2. Department of Hospital Pharmacy, University of Toyama, Toyama 930-0194, Japan

3. Instituto de Investigaciones Químicas, C.S.I.C-Universidad de Sevilla, Américo Vespucio 49, 41092 Seville, Spain

Funder

Ministerio de Economía y Competitividad

Japan Society for the Promotion of Science

Consejería de Economía y Conocimiento, Junta de Andalucía

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.8b01073

Reference63 articles.

1. Recent structural insights into the expanding world of carbohydrate-active enzymes

2. Iminosugars as therapeutic agents: recent advances and promising trends

3. Iminosugars

4. Recent Developments of Transition-State Analogue Glycosidase Inhibitors of Non-Natural Product Origin

5. Naturally Occurring Iminosugars and Related Compounds: Structure, Distribution, and Biological Activity

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