Microdroplet Chemistry Accelerating a Three-Component Passerini Reaction for α-Acyloxy Carboxamide Synthesis
Author:
Affiliation:
1. College of Material, Chemistry and Chemical Engineering, Key Laboratory of Organosilicon Chemistry and Material Technology, Ministry of Education, Hangzhou Normal University, 2318 Yuhangtang Road, Hangzhou 311121, China
Funder
National Natural Science Foundation of China
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.joc.3c01206
Reference78 articles.
1. Small Heterocycles in Multicomponent Reactions
2. Expanding the Chemical Space of Drug-like Passerini Compounds: Can α-Acyloxy Carboxamides Be Considered Hard Drugs?
3. Multicomponent synthesis of α-acylamino and α-acyloxy amide derivatives of desmycosin and their activity against gram-negative bacteria
4. Design, synthesis and biological evaluation of novel α-acyloxy carboxamides via Passerini reaction as caspase 3/7 activators
5. Novel peptidomimetic compounds containing redox active chalcogens and quinones as potential anticancer agents
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1. Mild Diarylmethylation of Indoles through Regioselective 1,6-Hydroarylation of para-Quinone Methides in Microdroplets/Thin Film;ACS Sustainable Chemistry & Engineering;2024-06-13
2. Photoredox radical cyclization reaction of o-vinylaryl isocyanides with acyl chlorides to access 2,4-disubstituted quinolines;Organic & Biomolecular Chemistry;2024
3. Is Reaction Acceleration of Microdroplet Chemistry Favorable to Controlling the Enantioselectivity?;The Journal of Organic Chemistry;2023-11-10
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