Transition-Metal-Mediated Chemo- and Stereoselective Total Synthesis of (−)-Galanthamine-Reference-Cited by-同舟云学术

Transition-Metal-Mediated Chemo- and Stereoselective Total Synthesis of (−)-Galanthamine

Published:2022-01-10 Issue:2 Volume:87 Page:1325-1334
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Miller Iain R.¹,McLean Neville J.¹,Moustafa Gamal A. I.¹,Ajavakom Vachiraporn¹,Kemp Stephen C.¹,Bellingham Richard K.²,Camp Nicholas P.³,Brown Richard C. D.¹^ORCID

Affiliation:

1. School of Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, U.K.

2. Chemical Development, Glaxo SmithKline Pharmaceuticals, The Old Powder Mills, Leigh, Tonbridge, Kent TN11 9AN, U.K.

3. Eli Lilly Research Centre, Erl Wood Manor, Sunninghill Road, Windlesham, Surrey GU20 6PH, U.K.

Funder

Engineering and Physical Sciences Research Council

Royal Society

University of Southampton

GlaxoSmithKline

Eli Lilly and Company

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.1c02638

Reference43 articles.

1. Amaryllidaceae andSceletiumalkaloids

2. Synthesis and Pharmacology of Galantamine

3. Chemical and pharmacological characterization of galanthamine, an acetylcholinesterase inhibitor, and its derivatives. A potential application in Alzheimer's disease?

4. Galantamine: Effect on nicotinic receptor binding, acetylcholinesterase inhibition, and learning

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