A Mild and Highly Diastereoselective Preparation of N-Alkenyl-2-Pyridones via 2-Halopyridinium Salts and Aldehydes

Author:

Shivers Grant N.1,Pigge F. Christopher1ORCID

Affiliation:

1. Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Reference43 articles.

1. A lesson for site-selective C–H functionalization on 2-pyridones: radical, organometallic, directing group and steric controls

2. Pyridones – Powerful Precursors for the Synthesis of Alkaloids, Their Derivatives, and Alkaloid-Inspired Compounds

3. Transition Metal‐Catalysed Direct C−H Bond Functionalizations of 2‐Pyridone Beyond C3‐Selectivity

4. Roehrig, S.; Hillisch, A.; Strassburger, J.; Heitmeier, S.; Schmidt, M. V.; Schlemmer, K.H.; Tersteegen, A.; Buchmueller, A.; Gerdes, C.; Schaefer, M.; Kinzel, T.; Teller, H.; Schirok, H.; Klar, J.; Jimenez Nunez, E. Preparation of substituted oxopyridine derivatives and use thereof in the treatment of cardiovascular disorders. WO 2014154794A1, 2014.

5. Jimenez Nunez, E.; Ackerstaff, J.; Roehrig, S.; Hillisch, A.; Meier, K.; Heitmeier, S.; Tersteegen, A.; Stampfuss, J.; Ellerbrock, P.; Meibom, D.; Lang, D. Preparation of substituted oxopyridine derivatives for the treatment and/or prophylaxis of diseases. WO 2017005725A1, 2017.

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