Synthesis of Sialyl LewisX Glycomimetics Bearing a Bicyclic 3-O,4-C-Fused Galactopyranoside Scaffold-Reference-Cited by-同舟云学术

Synthesis of Sialyl LewisX Glycomimetics Bearing a Bicyclic 3-O,4-C-Fused Galactopyranoside Scaffold

Published:2019-05-15 Issue:11 Volume:84 Page:7372-7387
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Simard Ryan D.¹²^ORCID,Joyal Mathieu³,Gillard Laura¹,Di Censo Gianna¹,Maharsy Wael³,Beauregard Janie³,Colarusso Pina⁴,Patel Kamala D.⁴,Prévost Michel¹^ORCID,Nemer Mona³,Guindon Yvan¹²³^ORCID

Affiliation:

1. Bio-Organic Chemistry Laboratory, Institut de Recherches Cliniques de Montréal, Montréal, Québec H2W 1R7, Canada

2. Department of Chemistry, Université de Montréal, Montréal, Québec H3C 3J7, Canada

3. Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada

4. Live Cell Imaging Laboratory, Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Alberta T2N 4N1, Canada

Funder

Natural Sciences and Engineering Research Council of Canada

Canadian Glycomics Network

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.9b01075

Reference53 articles.

1. From carbohydrate leads to glycomimetic drugs

2. Selectin−Carbohydrate Interactions: From Natural Ligands to Designed Mimics

3. The discovery, biology, and drug development of sialyl Lea and sialyl Lex

4. Acyclic Tethers Mimicking Subunits of Polysaccharide Ligands: Selectin Antagonists

5. Endothelial-Leukocyte Adhesion Molecules

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