Studies on the Configurational Stability of Tropolone-Ketone-, Ester-, and Aldehyde-Based Chiral Axes-Reference-Cited by-同舟云学术

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Studies on the Configurational Stability of Tropolone-Ketone-, Ester-, and Aldehyde-Based Chiral Axes

Published:2023-12-22 Issue:1 Volume:89 Page:541-552
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Baucom John-Charles¹²,Agyemang Nana B.¹²,Trelles Theresa¹,Gallicchio Emilio¹²³^ORCID,Murelli Ryan P.¹²³^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, Brooklyn College, The City University of New York, Brooklyn, New York 11210, United States

2. PhD Program in Chemistry, The Graduate Center of the City University of New York, New York, New York 10016, United States

3. PhD Program in Biochemistry, The Graduate Center of the City University of New York, New York, New York 10016, United States

Funder

National Institute of General Medical Sciences

National Science Foundation

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.3c02286

Reference44 articles.

1. Discovery of 6-Fluoro-5-(R)-(3-(S)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)-2-methylphenyl)-2-(S)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton’s Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked Atropisomers

2. Atropisomerism Observed in Indometacin Derivatives

3. Conformation and Atropisomeric Properties of Indometacin Derivatives

4. Synthesis and evaluation of Apogossypol atropisomers as potential Bcl-xL antagonists

5. Leveraging Atropisomerism to Obtain a Selective Inhibitor of RET Kinase with Secondary Activities toward EGFR Mutants

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