Noncovalent Interactions of Fluorine with Amide and CH2 Groups in N-Phenyl γ-Lactams: Covalently Identical Fluorine Atoms in Nonequivalent Chemical Environments-Reference-Cited by-同舟云学术

Noncovalent Interactions of Fluorine with Amide and CH2 Groups in N-Phenyl γ-Lactams: Covalently Identical Fluorine Atoms in Nonequivalent Chemical Environments

Published:2018-09-05 Issue:19 Volume:83 Page:11586-11594
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Xi Ning¹²³^ORCID,Sun Xiaohua¹,Li Minxiong²,Sun Mingming²,Xi Michael A.³,Zhan Zeping²,Yao Jia²,Bai Xu¹^ORCID,Wu Yanjun²,Liao Min²

Affiliation:

1. The School of Pharmaceutical Sciences, Jilin University, 1266 Fujin Road, Changchun, Jilin 130021, China

2. Sunshine Lake Pharmaceutical Co., Ltd, Dongyangguang Hi-tech Park, Dongguan, Guangdong 523871, China

3. Calitor Sciences LLC, PO Box 19185, Newbury Park, California 91319-9185, United States

Funder

Ministry of Science and Technology of the People's Republic of China

Guangdong Province

State Key Laboratory of Anti-Infective Drug Development, Sunshine Lake Pharma Co., Ltd.

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.8b01562

Reference25 articles.

1. Applications of Fluorine in Medicinal Chemistry

2. Fluorine in Pharmaceuticals: Looking Beyond Intuition

3. Fluorine Bonding — How Does It Work In Protein−Ligand Interactions?

4. Fluorine-Protein Interactions and 19F NMR Isotropic Chemical Shifts: An Empirical Correlation with Implications for Drug Design

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