Synthesis and Evaluation of Agelastatin Derivatives as Potent Modulators for Cancer Invasion and Metastasis
Author:
Affiliation:
1. Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States
Funder
Tufts Medical Center
Amgen
U.S. Department of Defense
National Institute of General Medical Sciences
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.joc.7b01162
Reference46 articles.
1. Agelastatin a, a new skeleton cytotoxic alkaloid of the oroidin family. Isolation from the axinellid sponge Agelas dendromorpha of the coral sea
2. Conformational Preferences and Absolute Configuration of Agelastatin A, a Cytotoxic Alkaloid of the Axinellid SpongeAgelas dendromorpha from the Coral Sea,via combined molecular modelling, NMR, and exciton splitting for diamide and hydroxyamide derivatives
3. The Active Centres of Agelastatin A, a Strongly Cytotoxic Alkaloid of the Coral Sea Axinellid SpongeAgelas dendromorpha, as Determined by Comparative Bioassays with Semisynthetic Derivatives
4. Antineoplastic Agents 470. Absolute Configuration of the Marine Sponge Bromopyrrole Agelastatin A1
5. Agelastatins C and D, New Pentacyclic Bromopyrroles from the Sponge Cymbastela sp., and Potent Arthropod Toxicity of (−)-Agelastatin A
Cited by 17 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Natural Compounds as Protease Inhibitors in Therapeutic Focus on Cancer Therapy;Anti-Cancer Agents in Medicinal Chemistry;2024-10
2. Highly Enantioselective Construction of the Polycyclic Piperazin-2-ones via NHC-Catalyzed [12 + 2] Cycloadditions;Organic Letters;2023-10-24
3. The N-Alkylation of Agelastatin A Modulates Its Chemical Reactivity;Molecules;2023-09-27
4. From Pyridine to (−)‐Agelastatin A;Advanced Synthesis & Catalysis;2023-07-04
5. The “cobra effect” in the imidazolinone series: how a donor can disable the nucleophilicity;Organic Chemistry Frontiers;2023
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3