Toward a Chemical Constructor: A Lego-Like Approach for Formal α-Alkylation of Cyclic Ketones-Reference-Cited by-同舟云学术

Toward a Chemical Constructor: A Lego-Like Approach for Formal α-Alkylation of Cyclic Ketones

Published:2024-05-20 Issue:11 Volume:89 Page:8208-8219
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Frolov Andriy I.¹²,Chuchvera Yaroslav O.¹,Ostapchuk Eugeniy N.¹²,Druzhenko Tetiana V.¹²,Volochnyuk Dmytro M.¹²³^ORCID,Ryabukhin Serhiy V.¹²³^ORCID

Affiliation:

1. Enamine Limited, 78 Winston Churchill Street, 02094 Kyiv, Ukraine

2. Taras Shevchenko National University of Kyiv, 60 Volodymyrska Street, 01601 Kyiv, Ukraine

3. Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Akademik Kuhar Street, 02660 Kyiv, Ukraine

Funder

Ministry of Education and Science of Ukraine

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.3c02628

Reference50 articles.

1. Qureshi, H. M.; Williams, R.; Marshall, C. Top 200 Small Molecule Pharmaceuticals by Retail Sales in 2021; https://njardarson.lab.arizona.edu/sites/njardarson.lab.arizona.edu/files/NjardarsonGroup2022SmallMoleculeTopPosterV3.pdf.

2. Structure and Reactivity of Lithium Enolates. From Pinacolone to SelectiveC-Alkylations of Peptides. Difficulties and Opportunities Afforded by Complex Structures

3. https://pubs.acs.org/.

4. α-Alkylation of Ketones with Alkenes Enabled by Photoinduced Activation of Silyl Enol Ethers in the Presence of a Small Amount of Water

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