The Chiron Approach to (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-ol, a Key Subunit of HIV-1 Protease Inhibitor Drug, Darunavir
Author:
Affiliation:
1. Department of Chemistry and Department of Medicinal Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907, United States
Funder
National Institutes of Health
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.joc.0c02396
Reference30 articles.
1. The effect of combined antiretroviral therapy on the overall mortality of HIV-infected individuals
2. Mortality of HIV-1-infected patients in the first year of antiretroviral therapy: comparison between low-income and high-income countries
3. Recent Progress in the Development of HIV-1 Protease Inhibitors for the Treatment of HIV/AIDS
4. Protease Inhibitors in AIDS Therapy; Ogden, R.; Flexner, C., Eds. Marcel Dekker: New York, 2001; pp 1–310.
5. FDA approves Darunavir on June 23, 2006: FDA approved new HIV treatment for patients who do not respond to existing drugs. Please see http://www.fda.gov/bbs/topics/NEWS/2006/NEW01395.html.
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