Highly Enantioselective Chiral Diol-Catalyzed Conjugate Addition of Boronic Acids to α,β-Unsaturated Trifluoromethyl Ketones-Reference-Cited by-同舟云学术

Highly Enantioselective Chiral Diol-Catalyzed Conjugate Addition of Boronic Acids to α,β-Unsaturated Trifluoromethyl Ketones

Published:2023-11-25 Issue:24 Volume:88 Page:17461-17471
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Hou Ya-Jing¹,Zhao Lu¹,Chai Guo-Li¹^ORCID,Zhong Kangbao¹,Chang Junbiao¹

Affiliation:

1. State Key Laboratory of Antiviral Drugs, Pingyuan Laboratory, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, China

Funder

the National Natural Science Foundation of China (NSFC)

the Henan Key Laboratory of Organic Functional Molecules and Drug Innovation

the Central Plains Scholars and Scientists Studio Fund

the Natural Science Foundation of Henan Province

the NMPA Key Laboratory for Research and Evaluation of Innovative Drug

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.3c02281

Reference49 articles.

1. Fluorine in Pharmaceuticals: Looking Beyond Intuition

2. Fluorination in Medicinal Chemistry: Methods, Strategies, and Recent Developments

3. The Many Roles for Fluorine in Medicinal Chemistry

4. Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design

5. Assessing the Bioisosterism of the Trifluoromethyl Group with a Protease Probe

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