Synthetic Evidence of the Amadori-Type Alkylation of Biogenic Amines by the Neurotoxic Metabolite Dopegal
Author:
Affiliation:
1. Van’t Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
http://pubs.acs.org/doi/pdf/10.1021/acs.joc.9b01948
Reference26 articles.
1. Neurotoxicity of MAO Metabolites of Catecholamine Neurotransmitters: Role in Neurodegenerative Diseases
2. Neurotoxicity and Metabolism of the Catecholamine-Derived 3,4-Dihydroxyphenylacetaldehyde and 3,4-Dihydroxyphenylglycolaldehyde: The Role of Aldehyde Dehydrogenase
3. Catecholamine autotoxicity. Implications for pharmacology and therapeutics of Parkinson disease and related disorders
4. Aggregation of α-synuclein by DOPAL, the monoamine oxidase metabolite of dopamine
5. Protein Reactivity of 3,4-Dihydroxyphenylacetaldehyde, a Toxic Dopamine Metabolite, Is Dependent on Both the Aldehyde and the Catechol
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