Direct Synthesis of α-Ketothioamide Derivatives through a One-Pot Reaction of Sulfur Ylides, Nitrosobenzenes, and Thioacetic Acid-Reference-Cited by-同舟云学术

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Direct Synthesis of α-Ketothioamide Derivatives through a One-Pot Reaction of Sulfur Ylides, Nitrosobenzenes, and Thioacetic Acid

Published:2024-06-07 Issue:12 Volume:89 Page:8878-8887
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Xiang Chaowei¹²,Luo Fang¹,Wang Zheng¹²,Pan Yunlong¹,Liu Yu¹,Zeng Linghui¹,Zhang Chong¹,Zhu Huajian¹²,Zhang Jiankang¹²,Shao Jiaan¹²^ORCID

Affiliation:

1. Key Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang Province, School of Medicine, Hangzhou City University, Hangzhou 310015, P. R. China

2. College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, P. R. China

Funder

Ministry of Education of the People's Republic of China

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.4c00738

Reference32 articles.

1. Recent advances in the Willgerodt–Kindler reaction

2. α-Ketothioamide Derivatives: A Promising Tool to Interrogate Phosphoglycerate Dehydrogenase (PHGDH)

3. Unravelling the Allosteric Targeting of PHGDH at the ACT-Binding Domain with a Photoactivatable Diazirine Probe and Mass Spectrometry Experiments

4. A practical and efficient synthesis of quinoxaline derivatives catalyzed by task-specific ionic liquid

5. Structure–Activity Relationships (SARs) of α-Ketothioamides as Inhibitors of Phosphoglycerate Dehydrogenase (PHGDH)

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