Organocatalytic Asymmetric Synthesis of SynVesT-1, a Synaptic Density Positron Emission Tomography Imaging Agent
Author:
Affiliation:
1. School of Chemistry, The Joseph Black Building, University of Glasgow, GlasgowG12 8QQ, U.K.
2. BHF-University Centre for Cardiovascular Science, University of Edinburgh, EdinburghEH16 4TJ, U.K.
Funder
British Heart Foundation
Wellcome Trust
University of Glasgow
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.joc.2c01895
Reference31 articles.
1. Puzzling Out Synaptic Vesicle 2 Family Members Functions
2. The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam
3. The Rise of Synaptic Density PET Imaging
4. Radiosynthesis of 11C-Levetiracetam: A Potential Marker for PET Imaging of SV2A Expression
5. Discovery of Heterocyclic Nonacetamide Synaptic Vesicle Protein 2A (SV2A) Ligands with Single-Digit Nanomolar Potency: Opening Avenues towards the First SV2A Positron Emission Tomography (PET) Ligands
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1. Association of synaptic density and cognitive performance in temporal lobe epilepsy: Humans and animals PET imaging study with [18F]SynVesT‐1;Psychiatry and Clinical Neurosciences;2024-05-28
2. Organocatalytic Asymmetric Synthesis of SynVesT-1 and [18F]-SynVesT-1;Synfacts;2022-12-16
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