Design, Synthesis, and Study of Lactam and Ring-Expanded Analogues of Teixobactin
Author:
Affiliation:
1. Department of Chemistry and Department of Pharmaceutical Sciences, University of California, Irvine, California 92697-2025, United States
Funder
National Institute of Allergy and Infectious Diseases
Allergan
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.joc.9b02631
Reference34 articles.
1. A new antibiotic kills pathogens without detectable resistance
2. Dual Targeting of Cell Wall Precursors by Teixobactin Leads to Cell Lysis
3. Lipid II as a target for antibiotics
4. X-ray Crystallographic Structure of a Teixobactin Derivative Reveals Amyloid-like Assembly
5. Gram-scale total synthesis of teixobactin promoting binding mode study and discovery of more potent antibiotics
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1. Structure–Activity Relationship Studies of the Peptide Antibiotic Clovibactin;The Journal of Organic Chemistry;2024-08-23
2. Investigation of Isobactin Analogues of Teixobactin;ACS Medicinal Chemistry Letters;2024-06-11
3. Supramolecular Interactions of Teixobactin Analogues in the Crystal State;The Journal of Organic Chemistry;2024-03-20
4. New Teixobactin Analogues with a Total Lactam Ring;ACS Medicinal Chemistry Letters;2023-11-14
5. Supramolecular Interactions of Teixobactin Analogues in the Crystal State;2023-11-01
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