A General Liquid–Liquid Partitioning Equation and Its Consequences: Learning from the pH Dependent Extraction of a Pharmaceutical Intermediate-Reference-Cited by-同舟云学术

A General Liquid–Liquid Partitioning Equation and Its Consequences: Learning from the pH Dependent Extraction of a Pharmaceutical Intermediate

Published:2018-03-19 Issue:7 Volume:83 Page:4270-4274
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Ashworth Ian W.¹^ORCID,Meadows Rebecca E.¹

Affiliation:

1. Pharmaceutical Technology & Development, AstraZeneca, S41/11 Etherow, Silk Road Business Park, Charter Way, Macclesfield, SK10 2NA, United Kingdom

Funder

AstraZeneca

FP7 Nanosciences, Nanotechnologies, Materials and new Production Technologies

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.8b00309

Reference21 articles.

1. Furniss, B. S.; Hannaford, A. J.; Smith, P. W. G.; Tatchell, A. R. Vogel’s Textbook of Practical Organic Chemistry, 5th ed. Longman: 1989; pp 156–160.

2. aAtherton, J. H.; Carpenter, K. J. Process Development: Physico-chemical Concepts; Oxford University Press: Oxford, 1999; pp 49–50.

3. Controlled pH Extraction in the Separation of Weak Acids and Bases

4. A microfluidic approach for flexible and efficient operation of a cross-coupling reactive flow

5. Recyclable NHC Catalyst for the Development of a Generalized Approach to Continuous Buchwald–Hartwig Reaction and Workup

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