A General Approach to Optically Pure, α-Methyl Non-Natural Amino Acids: Enabling Unique Peptides as Drug Candidates-Reference-Cited by-同舟云学术

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A General Approach to Optically Pure, α-Methyl Non-Natural Amino Acids: Enabling Unique Peptides as Drug Candidates

Published:2024-02-09 Issue:5 Volume:89 Page:3211-3213
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Passley Kyle D.¹^ORCID,Ruble J. Craig²,Kerr Mark S.³,Organ Michael G.¹^ORCID

Affiliation:

1. Centre for Catalysis Research and Innovation (CCRI), Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada

2. Discovery Chemistry Research and Technologies, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana 46285, United States

3. Synthetic Molecule Design and Development, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana 46285, United States

Funder

Natural Sciences and Engineering Research Council of Canada

Eli Lilly and Company

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.3c02677

Reference13 articles.

1. Comparative genomic analysis of human and chimpanzee proteases

2. A Comprehensive Review on Current Advances in Peptide Drug Development and Design

3. Trends in peptide drug discovery

4. Peptide Backbone Composition and Protease Susceptibility: Impact of Modification Type, Position, and Tandem Substitution

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