ent-Beyerane Diterpenes as a Key Platform for the Development of ArnT-Mediated Colistin Resistance Inhibitors

Author:

Quaglio Deborah1,Mangoni Maria Luisa2ORCID,Stefanelli Roberta34,Corradi Silvia15,Casciaro Bruno5,Vergine Valeria1,Lucantoni Federica3,Cavinato Luca3,Cammarone Silvia1,Loffredo Maria Rosa2,Cappiello Floriana2,Calcaterra Andrea1,Erazo Silvia6,Ghirga Francesca5ORCID,Mori Mattia7ORCID,Imperi Francesco4,Ascenzioni Fiorentina3,Botta Bruno1ORCID

Affiliation:

1. Department of Chemistry and Technology of Drugs, “Department of Excellence 2018−2022”, Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy

2. Laboratory Affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy

3. Department of Biology and Biotechnology Charles Darwin, Sapienza University of Rome, Laboratory Affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Via dei Sardi 70, 00185 Rome, Italy

4. Department of Science, Roma Tre University, Viale Guglielmo Marconi 446, 00146 Rome, Italy

5. Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Viale Regina Elena, 291, 00161 Rome, Italy

6. Department of Pharmacological and Toxicological Chemistry, Faculty of Chemical and Pharmaceutical Sciences, University of Chile, 1058 Santiago, Chile

7. Department of Biotechnology, Chemistry and Pharmacy, “Department of Excellence 2018−2022”, University of Siena, via Aldo Moro 2, 53100 Siena, Italy

Funder

Universit? degli Studi di Siena

Sapienza Universit? di Roma

Fondazione per la Ricerca sulla Fibrosi Cistica

Istituto Pasteur-Fondazione Cenci Bolognetti

Ministero dell'Istruzione, dell'Universit? e della Ricerca

PON (Piano Operativo Nazionale)

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

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