Divergent Nine-Step Syntheses of Perhydrohistrionicotoxin Analogs and Their Inhibition Activity Toward Chicken α4β2-Neuronal Nicotinic Acetylcholine Receptors-Reference-Cited by-同舟云学术

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Divergent Nine-Step Syntheses of Perhydrohistrionicotoxin Analogs and Their Inhibition Activity Toward Chicken α4β2-Neuronal Nicotinic Acetylcholine Receptors

Published:2024-02-26 Issue:6 Volume:89 Page:4128-4133
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Nishikawa Keisuke¹^ORCID,Ono Yosuke¹,Mori Sumito²,Takayama Koichi²^ORCID,Ihara Makoto²,Matsuda Kazuhiko²^ORCID,Morimoto Yoshiki¹

Affiliation:

1. Department of Chemistry, Graduate School of Science, Osaka Metropolitan University, Osaka 558-8585, Japan

2. Department of Applied Biological Chemistry, Faculty of Agriculture, Kindai University, Nara 631-8505, Japan

Funder

Astellas Foundation for Research on Metabolic Disorders

Japan Society for the Promotion of Science

Saneyoshi Scholarship Foundation

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.3c02988

Reference47 articles.

1. Histrionicotoxins: Roentgen-Ray Analysis of the Novel Allenic and Acetylenic Spiroalkaloids Isolated from a Colombian Frog, Dendrobates histrionicus

2. Histrionicotoxin enhances agonist-induced desensitization of acetylcholine receptor.

3. Distinct protein components from Torpedo marmorata membranes carry the acetylcholine receptor site and the binding site for local anesthetics and histrionicotoxin.

4. Nicotinic receptor-elicited sodium flux in rat pheochromocytoma PC12 cells: Effects of agonists, antagonists, and noncompetitive blockers

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