Copper-Catalyzed Reductive Ring-Cleavage of Isoxazoles: Synthesis of Fluoroalkylated Enaminones and Application for the Preparation of Celecoxib, Deracoxib, and Mavacoxib-Reference-Cited by-同舟云学术

Copper-Catalyzed Reductive Ring-Cleavage of Isoxazoles: Synthesis of Fluoroalkylated Enaminones and Application for the Preparation of Celecoxib, Deracoxib, and Mavacoxib

Published:2021-02-15 Issue:6 Volume:86 Page:4557-4566
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Wan Chao¹,Pang Jian-Yu¹,Jiang Wei²^ORCID,Zhang Xiao-Wei¹³^ORCID,Hu Xiang-Guo¹⁴^ORCID

Affiliation:

1. National Engineering Research Center for Carbohydrate Synthesis, Jiangxi Normal University, Nanchang, Jiangxi 330022, PR China

2. Research Center for Traditional Chinese Medicine Resources and Ethnic Minority Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi 330006, PR China

3. School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng, Shandong 252059, China

4. Key Laboratory of Small Functional Organic Molecule, Ministry of Education, Jiangxi Normal University, Nanchang, Jiangxi 330022, PR China

Funder

Natural Science Foundation of Jiangxi Province

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.0c02980

Reference59 articles.

1. Fluorine in medicinal chemistry