Chemo- and Diastereoselective Cycloisomerization/[2 + 3] Cycloaddition of Enynamides: Synthesis of Spiropyrazolines as Potential Anticancer Reagents-Reference-Cited by-同舟云学术

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Chemo- and Diastereoselective Cycloisomerization/[2 + 3] Cycloaddition of Enynamides: Synthesis of Spiropyrazolines as Potential Anticancer Reagents

Published:2023-05-05 Issue:11 Volume:88 Page:7311-7319
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Fang Huaying¹,Li Yang¹,Zhang Lan²^ORCID,Yan Zhen-Hui¹,Ma Ke¹,Peng Cheng¹^ORCID,Huang Wei¹^ORCID,Zhan Gu¹^ORCID

Affiliation:

1. State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China

2. Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China

Funder

Chengdu University of Traditional Chinese Medicine

Department of Science and Technology of Sichuan Province

National Health Commission of the People's Republic of China

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.3c00533

Reference37 articles.

1. Recently reported biological activities of pyrazole compounds

2. A close look into the biological and synthetic aspects of fused pyrazole derivatives

3. Spirocyclic Scaffolds in Medicinal Chemistry

4. Preparation of New Spiropyrazole, Pyrazole and Hydantoin Derivatives and Investigation of Their Antioxidant and Antibacterial Activities.

5. Isolation of three new metabolites and intervention of diazomethane led to separation of compound 1 & 2 from an endophytic fungus, Cryptosporiopsis sp. depicting cytotoxic activity

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1. Asymmetric construction of enantioenriched furo[2,3-b]pyridines through sequential gold, palladium/phosphoric acid catalysis;Organic Chemistry Frontiers;2024

2. Palladium-Catalyzed Aerobic Oxidative Spirocyclization of Alkyl Amides with Maleimides via β-C(sp³)–H Activation;Organic Letters;2023-08-22

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