Direct 1,6-Difluoromethylation of 3-Methyl-4-nitro-5-styryl Isoxazoles by Photoredox-Promoted Radical Addition

Author:

Zheng Jianli12,Xu Yingqian1,Song Shaorui1,Huang Ling1,Cao Dongdong1,Zhong Aiguo1,Yang Jianguo1ORCID,Chen Dingben123ORCID

Affiliation:

1. School of Pharmaceutical and Chemical Engineering, Taizhou University, 1139 Shifu Road, Taizhou 318000, China

2. Department of Chemistry, Zhejiang Sci-Tech University, Xiasha West Higher Education District, Hangzhou 310018, China

3. Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China

Funder

Natural Science Foundation of Zhejiang Province

Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Reference52 articles.

1. Fluorine in medicinal chemistry

2. bHiyama, T.; Kanie, K.; Kusumoto, T.; Morizawa, T. Y.; Shimizu, M. Organofluorine Compounds: Chemistry and Applications; Springer: Berlin, 2000; pp 137–228.

3. New fluorinated functional materials

4. Fluorinated Pyrazoles: From Synthesis to Applications

5. 18F-Labeling of Arenes and Heteroarenes for Applications in Positron Emission Tomography

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