PPM Ir-f-phamidol-Catalyzed Asymmetric Hydrogenation of γ-Amino Ketones Followed by Stereoselective Cyclization for Construction of Chiral 2-Aryl-pyrrolidine Pharmacophores

Author:

Yin Congcong12,Zhang Runtong13,Pan Yingmin1,Gao Shuang1,Ding Xiaobing1,Bai Shao-Tao3ORCID,Lang Qiwei1,Zhang Xumu1ORCID

Affiliation:

1. Department of Chemistry and Department of Chemistry and Medi-X PingShan, Southern University of Science and Technology, Shenzhen 518055, China

2. Research Center of Green Pharmaceutical Technology and Process, Hubei Key Laboratory of Natural Products Research and Development, College of Biological and Pharmaceutical Sciences, China Three Gorges University, Yichang 443002, China

3. Center for Carbon-Neutrality Catalysis and Engineering and Institute of Carbon-Neutral Technology, Shenzhen Polytechnic University, Shenzhen 518055, China

Funder

the Research Projects of Department of Education of Guangdong Province

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

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