1,3-Diaza-Claisen Rearrangements of Vinyl Pyrrolidines Tethered to In Situ Generated Carbodiimides Afford Ring-Expanded [9,5]- and [9,6]-Bicyclic Guanidines
Author:
Affiliation:
1. Department of Chemistry, University of Vermont, Burlington, Vermont 05405, United States
Funder
Division of Chemistry
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.joc.2c02524
Reference48 articles.
1. A 1,3-Diaza-Claisen Rearrangement that Affords Guanidines
2. Structure–Reactivity Relationships of Zwitterionic 1,3-Diaza-Claisen Rearrangements
3. Optimization of methods for the generation of carbodiimides for zwitterionic 1,3-diaza-Claisen rearrangements
4. Intramolecular Formation of Zwitterionic Intermediates in 1,3-Diaza-Claisen Rearrangements
5. Broadening the Scope of the Zwitterionic 1,3-Diaza-Claisen Rearrangement through a Tethering Strategy
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1. Crystal structures of sulfonamide protected bicyclic guanidines: (S)-8-{[(tert-butyldimethylsilyl)oxy]methyl}-1-[(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl]-1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidin-1-ium trifluoromethanesulfonate and (S)-8-(iodomethyl)-1-tosyl-1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidin-1-ium iodide;Acta Crystallographica Section E Crystallographic Communications;2024-02-20
2. One-pot four-component synthesis of novel isothiourea-ethylene-tethered-piperazine derivatives;RSC Advances;2023
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