Enabling, Decagram-Scale Synthesis of Macrocyclic MCL-1 Inhibitor ABBV-467-Reference-Cited by-同舟云学术

Enabling, Decagram-Scale Synthesis of Macrocyclic MCL-1 Inhibitor ABBV-467

Published:2023-11-01 Issue:22 Volume:88 Page:15562-15568
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Brady Patrick B.¹^ORCID,Sorensen Bryan K.¹,Risi Roberto M.¹,Curtin Michael L.¹,Mantei Robert A.¹,Florjancic Alan S.¹,Mastracchio Anthony²^ORCID,Ji Cheng²,Kunzer Aaron R.²,Lai Chunqiu¹,Storer Gregory E.³^ORCID,Chan Vincent S.³,Henry Rodger F.⁴,Souers Andrew J.⁵,Michaelides Michael R.⁵,Judd Andrew S.²^ORCID,Hansen T. Matthew¹

Affiliation:

1. Centralized Organic Synthesis Group, Small Molecule Therapeutic and Platform Technologies, AbbVie Inc., North Chicago, Illinois 60064, United States

2. Global Medicinal Chemistry, Small Molecule Therapeutic and Platform Technologies, AbbVie, Inc., North Chicago, Illinois 60064, United States

3. Center of Catalysis, Process Research and Development, AbbVie, Inc., North Chicago, Illinois 60064, United States

4. Analytical Sciences, Small Molecule Therapeutic and Platform Technologies, AbbVie Inc., North Chicago, Illinois 60064, United States

5. Oncology Discovery, AbbVie, Inc., North Chicago, Illinois 60064, United States

Funder

AbbVie

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.3c00939

Reference40 articles.

1. The Hallmarks of Cancer

2. Proliferation, cell cycle and apoptosis in cancer

3. New frontiers in promoting tumour cell death: targeting apoptosis, necroptosis and autophagy

4. The Bcl-2 apoptotic switch in cancer development and therapy

5. The BCL-2 protein family: opposing activities that mediate cell death

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Bis(bicyclo[1.1.1]pentyl)chlorophosphine as a Precursor for the Preparation of Bis(bicyclo[1.1.1]pentyl)phosphines;Organic Letters;2024-05-12