Synthesis and Biological Evaluation of 6-[(1R)-1-Hydroxyethyl]-2,4a(R),6(S),8a(R)-tetrahydropyrano-[3,2-b]-pyran-2-one and Structural Analogues of the Putative Structure of Diplopyrone-Reference-Cited by-同舟云学术

Synthesis and Biological Evaluation of 6-[(1R)-1-Hydroxyethyl]-2,4a(R),6(S),8a(R)-tetrahydropyrano-[3,2-b]-pyran-2-one and Structural Analogues of the Putative Structure of Diplopyrone

Published:2018-12-14 Issue:2 Volume:84 Page:666-678
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Lazzara Nicholas C.¹,Rosano Robert J.¹,Vagadia Purav P.¹,Giovine Matthew T.¹,Bezpalko Mark W.¹,Piro Nicholas A.¹,Kassel Wm. Scott¹^ORCID,Boyko Walter J.¹,Zubris Deanna L.¹^ORCID,Schrader Kevin K.²,Wedge David E.²,Duke Stephen O.²^ORCID,Giuliano Robert M.¹^ORCID

Affiliation:

1. Department of Chemistry, Villanova University, Villanova, Pennsylvania 19085, United States

2. Natural Products Utilization Research Unit, Agricultural Research Service, U.S. Department of Agriculture, P.O. Box 1848, University, Mississippi 38677, United States

Funder

Villanova University

U.S. Department of Agriculture

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.8b02490

Reference56 articles.

1. Diplopyrone, a New Phytotoxic Tetrahydropyranpyran-2-one Produced by Diplodia mutila, a Fungus Pathogen of Cork Oak

2. Assignment of the Absolute Configuration of (+)-Diplopyrone, the Main Phytotoxin Produced by Diplodia mutila, the Pathogen of the Cork Oak Decline, by a Nonempirical Analysis of Its Chiroptical Properties