Crystal Structure of Human DT-diaphorase: A Model for Interaction with the Cytotoxic Prodrug 5-(Aziridin-1-yl)-2,4-dinitrobenzamide (CB1954)-Reference-Cited by-同舟云学术

Crystal Structure of Human DT-diaphorase: A Model for Interaction with the Cytotoxic Prodrug 5-(Aziridin-1-yl)-2,4-dinitrobenzamide (CB1954)

Published:1999-09-29 Issue:21 Volume:42 Page:4325-4330
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Skelly Jane V.¹,Sanderson Mark R.¹,Suter David A.¹,Baumann Ulrich¹,Read Martin A.¹,Gregory David S. J.¹,Bennett Matthew¹,Hobbs Stephen M.¹,Neidle Stephen¹

Affiliation:

1. CRC Biomolecular Structure Unit and CRC Centre for Cancer Therapeutics, The Institute of Cancer Research, Cotswold Road, Sutton, Surrey SM2 5NG, U.K., and Randall Institute, Kings College London, 26-29 Drury Lane, London WC2B 5RL, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm991060m

Reference27 articles.

1. Induction of NAD(P)H:quinone reductase in murine hepatoma cells by phenolic antioxidants, azo dyes, and other chemoprotectors: a model system for the study of anticarcinogens.

2. Cytosolic NAD(P)H:(Quinone-acceptor)oxidoreductase in human normal and tumor tissue: Effects of cigarette smoking and alcohol

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