1. Department of Cancer Biology, Biostatistics Shared Resource at Vanderbilt-Ingram Cancer Center and Department of Biostatistics, Mass Spectrometry Research Center and Department of Biochemistry, Microarray Shared Resources and Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee 37232, and Shanghai Center for Bioinformation Technology, 100 Qinzhou Rd., Fl. 12, Shanghai, 200235, Peoples Republic of China