QSAR Models for Predicting in Vivo Aquatic Toxicity of Chlorinated Alkanes to Fish

Author:

Zvinavashe Elton1,van den Berg Hans1,Soffers Ans E. M. F.1,Vervoort Jacques1,Freidig Andreas1,Murk Albertinka J.1,Rietjens Ivonne M. C. M.1

Affiliation:

1. Division of Toxicology, Wageningen University, Tuinlaan 5, 6703 HE Wageningen, Division of Biochemistry, Wageningen University, Dreijenlaan 3, 6703 HA Wageningen, Division of Kinetics and Metabolism, The Netherlands Organization for Applied Scientific Research (TNO) Quality of Life, Utrechtseweg 48, P.O. Box 360, 3700 AJ Zeist, and Wageningen University/TNO Centre for Food Toxicology, P.O. Box 8000, 6700 EA, Wageningen, The Netherlands

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Reference27 articles.

1. Organization for Economic Cooperation and Development (OECD) (2007) Guidance document on the validation of (quantitative) structure−activity relationships [(Q)SAR] models.OECD Environment Health and Safety Publications: Series on Testing and Assessment No. 69, pp 1–154, OECD Environment Directorate, Paris; ENV/JM/MONO(2007)2.

2. National Research Council (NRC) (1993) In Situ Bioremediation: When Does it Work? p33,The National Academy Press,Washington, DC.

3. Improved QSARs for predictive toxicology of halogenated hydrocarbons

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