Highly Potent and Selective Nonsteroidal Dual Inhibitors of CYP17/CYP11B2 for the Treatment of Prostate Cancer To Reduce Risks of Cardiovascular Diseases-Reference-Cited by-同舟云学术

Highly Potent and Selective Nonsteroidal Dual Inhibitors of CYP17/CYP11B2 for the Treatment of Prostate Cancer To Reduce Risks of Cardiovascular Diseases

Published:2013-07-29 Issue:15 Volume:56 Page:6101-6107
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Pinto-Bazurco Mendieta Mariano A. E.¹,Hu Qingzhong¹,Engel Matthias¹,Hartmann Rolf W.¹

Affiliation:

1. Pharmaceutical and Medicinal Chemistry, Saarland University & Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Campus C2-3, D-66123 Saarbrücken, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm400484p

Reference52 articles.

1. Significant and Sustained Antitumor Activity in Post-Docetaxel, Castration-Resistant Prostate Cancer With the CYP17 Inhibitor Abiraterone Acetate

2. Phase I Clinical Trial of a Selective Inhibitor of CYP17, Abiraterone Acetate, Confirms That Castration-Resistant Prostate Cancer Commonly Remains Hormone Driven

3. cYin, L.; Hu, Q.CYP17 inhibitors: from promiscuous abiraterone to selective C17-20 lyase inhibitors and multi-targeting agents.Nat. Rev. Urol. 2013, in press

4. Recent Progress in Pharmaceutical Therapies for Castration-Resistant Prostate Cancer

5. Complications of androgen deprivation therapy in prostate cancer

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