Synthesis of 7200 Small Molecules Based on a Substructural Analysis of the Histone Deacetylase Inhibitors Trichostatin and Trapoxin-Reference-Cited by-同舟云学术

Synthesis of 7200 Small Molecules Based on a Substructural Analysis of the Histone Deacetylase Inhibitors Trichostatin and Trapoxin

Published:2001-11-30 Issue:26 Volume:3 Page:4239-4242
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Sternson Scott M.¹,Wong Jason C.¹,Grozinger Christina M.¹,Schreiber Stuart L.¹

Affiliation:

1. Howard Hughes Medical Institute (HHMI), Institute of Chemistry and Cell Biology (ICCB), Department of Chemistry & Chemical Biology, Harvard University, Cambridge, Massachusetts 02138

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ol016915f

Reference23 articles.

1. Acetylation: a regulatory modification to rival phosphorylation?

2. Split−Pool Synthesis of 1,3-Dioxanes Leading to Arrayed Stock Solutions of Single Compounds Sufficient for Multiple Phenotypic and Protein-Binding Assays

3. Nuclear histone acetylases and deacetylases and transcriptional regulation: HATs off to HDACs

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