Separation of Racemic Bicalutamide by an Optimized Combination of Continuous Chromatography and Selective Crystallization-Reference-Cited by-同舟云学术

Separation of Racemic Bicalutamide by an Optimized Combination of Continuous Chromatography and Selective Crystallization

Published:2011-10-26 Issue:2 Volume:16 Page:331-342
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Kaemmerer Henning¹,Horvath Zoltan,Lee Ju Weon,Kaspereit Malte,Arnell Robert²,Hedberg Martin²,Herschend Björn²,Jones Matthew J.²,Larson Kerstin²,Lorenz Heike,Seidel-Morgensten Andreas

Affiliation:

1. Evonik Industries AG, 63457 Hanau, Germany

2. AstraZeneca R&D Södertälje, Pharmaceutical Development, 15185 Södertälje, Sweden

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op200136z

Reference35 articles.

1. Thijs, L.U.S. Pat. Appl. 2003/0073742, 2003.

2. Resolution of the non steroidal antiandrogen 4'-cyano-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl-3'-(trifluoromethyl)propionanilide and the determination of the absolute configuration of the active enantiomer

3. Sörös, B.WO 01/00608, 2006.

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