Retinoic Acid-Elicited RARα/RXRα Signaling Attenuates Aβ Production by Directly Inhibiting γ-Secretase-Mediated Cleavage of Amyloid Precursor Protein-Reference-Cited by-同舟云学术

Retinoic Acid-Elicited RARα/RXRα Signaling Attenuates Aβ Production by Directly Inhibiting γ-Secretase-Mediated Cleavage of Amyloid Precursor Protein

Published:2013-04-15 Issue:7 Volume:4 Page:1093-1100
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Kapoor Arun¹²,Wang Bo-Jeng³,Hsu Wen-Ming⁴,Chang Ming-Yun,Liang Shu-Mei,Liao Yung-Feng²

Affiliation:

1. Molecular and Biological Agricultural Sciences Program, Taiwan International Graduate Program, National Chung-Hsing University and Academia Sinica, Taipei 11529, Taiwan

2. Graduate Institute of Biotechnology and Department of Life Sciences, National Chung-Hsing University, Taichung 402, Taiwan

3. Institute of Zoology, National Taiwan University, Taipei 106, Taiwan

4. Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei 100, Taiwan

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/cn400039s

Reference43 articles.

1. Alzheimer's Disease

2. Proteolytic processing and cell biological functions of the amyloid precursor protein

3. Alzheimer's Disease: Genes, Proteins, and Therapy

4. Amyloid Precursor Protein Trafficking, Processing, and Function

5. γ-secretases: from cell biology to therapeutic strategies

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