Cell-Based Medicinal Chemistry Optimization of High Throughput Screening Hits for Orally Active Antimalarials. Part 2: Hits from SoftFocus Kinase and other Libraries-Reference-Cited by-同舟云学术

Cell-Based Medicinal Chemistry Optimization of High Throughput Screening Hits for Orally Active Antimalarials. Part 2: Hits from SoftFocus Kinase and other Libraries

Published:2013-08-30 Issue:20 Volume:56 Page:7750-7754
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Younis Yassir¹,Street Leslie J.¹,Waterson David²,Witty Michael J.²,Chibale Kelly¹³

Affiliation:

1. Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa

2. Medicines for Malaria Venture, ICC, Route de Pré-Bois 20, PO Box 1826, 1215 Geneva, Switzerland

3. Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Rondebosch 7701, South Africa

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm400279y

Reference13 articles.

1. World Malaria Report 2012;World Health Organization:Geneva, Switzerland, 2012.

2. New Targets, New Hope: Novel Drug Targets for Curbing Malaria

3. The State of the Art in Anti-Malarial Drug Discovery and Development

4. Thousands of chemical starting points for antimalarial lead identification

5. Chemical genetics of Plasmodium falciparum

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