Synthesis and Biological Evaluation of 2-Aryliminopyrrolidines as Selective Ligands for I1 Imidazoline Receptors: Discovery of New Sympatho-Inhibitory Hypotensive Agents with Potential Beneficial Effects in Metabolic Syndrome-Reference-Cited by-同舟云学术

Synthesis and Biological Evaluation of 2-Aryliminopyrrolidines as Selective Ligands for I1 Imidazoline Receptors: Discovery of New Sympatho-Inhibitory Hypotensive Agents with Potential Beneficial Effects in Metabolic Syndrome

Published:2014-12-31 Issue:2 Volume:58 Page:878-887
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gasparik Vincent¹,Greney Hugues¹,Schann Stephan¹,Feldman Josiane¹,Fellmann Lyne¹,Ehrhardt Jean-Daniel¹,Bousquet Pascal¹

Affiliation:

1. Laboratoire de Neurobiologie et Pharmacologie Cardiovasculaire, Faculté de Médecine, EA 7296, Fédération de Médecine Translationnelle, Université de Strasbourg, 11 rue Humann, 67000 Strasbourg, France

Funder

Institut de Recherche International Servier

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm501456p

Reference71 articles.

1. I1 receptors, cardiovascular function, and metabolism

2. I1 Imidazoline Receptors Involved in Cardiovascular Regulation: Where Are We and Where Are We Going?

3. Imidazoline Receptors, Novel Agents and Therapeutic Potential