Complexes of Bacterial Nicotinate Mononucleotide Adenylyltransferase with Inhibitors: Implication for Structure-Based Drug Design and Improvement-Reference-Cited by-同舟云学术

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Complexes of Bacterial Nicotinate Mononucleotide Adenylyltransferase with Inhibitors: Implication for Structure-Based Drug Design and Improvement

Published:2010-06-25 Issue:14 Volume:53 Page:5229-5239
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Huang Nian¹,Kolhatkar Rohit²,Eyobo Yvonne¹,Sorci Leonardo³,Rodionova Irina³,Osterman Andrei L.³,MacKerell Alexander D.²,Zhang Hong¹

Affiliation:

1. Department of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390

2. Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, 20 Penn Street, Baltimore, Maryland 21201

3. The Burnham Institute for Medical Research, La Jolla, California 92037

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm100377f

Reference41 articles.

1. The fallacies of hope: will we discover new antibiotics to combat pathogenic bacteria in time?

2. New strategies for combating multidrug-resistant bacteria

3. Antibiotics for Emerging Pathogens

4. Exploiting genomics to discover new antibiotics

5. From Genetic Footprinting to Antimicrobial Drug Targets: Examples in Cofactor Biosynthetic Pathways

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1. Synthesis, Biological, and Computational Evaluations of Conformationally Restricted NAD-Mimics as Discriminant Inhibitors of Human NMN-Adenylyltransferase Isozymes;Pharmaceuticals;2024-06-06

2. Inhibitors of NAD+ Production in Cancer Treatment: State of the Art and Perspectives;International Journal of Molecular Sciences;2024-02-08

3. First series of N-alkylamino peptoid homooligomers: solution phase synthesis and conformational investigation;Beilstein Journal of Organic Chemistry;2022-07-14

4. Expression, Purification, and Biophysical Characterization of Klebsiella Pneumoniae Nicotinate Nucleotide Adenylyltransferase;The Protein Journal;2022-01-27

5. In silico repurposing of a Novobiocin derivative for activity against latency associated Mycobacterium tuberculosis drug target nicotinate-nucleotide adenylyl transferase (Rv2421c);PLOS ONE;2021-11-02

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