Discovery of Tankyrase Inhibiting Flavones with Increased Potency and Isoenzyme Selectivity

Author:

Narwal Mohit12,Koivunen Jarkko3,Haikarainen Teemu1,Obaji Ezeogo1,Legala Ongey E.1,Venkannagari Harikanth1,Joensuu Päivi4,Pihlajaniemi Taina3,Lehtiö Lari1

Affiliation:

1. Department of Biochemistry and Biocenter Oulu, University of Oulu, Oulu 90570, Finland

2. Pharmaceutical Sciences, Department of Biosciences, Abo Akademi University, Turku FI-20500, Finland

3. Center for Cell-Matrix Research and Biocenter Oulu, Department of Medical Biochemistry and Molecular Biology, University of Oulu, Oulu 90570, Finland

4. Department of Chemistry, University of Oulu, Oulu 90570, Finland

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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