Efficient and Scalable Enantioselective Synthesis of a CGRP Antagonist-Reference-Cited by-同舟云学术

Efficient and Scalable Enantioselective Synthesis of a CGRP Antagonist

Published:2012-09-06 Issue:18 Volume:14 Page:4938-4941
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Leahy David K.¹,Fan Yu¹,Desai Lopa V.¹,Chan Collin¹,Zhu Jason¹,Luo Guanglin¹,Chen Ling¹,Hanson Ronald L.¹,Sugiyama Masano¹,Rosner Thorsten¹,Cuniere Nicolas¹,Guo Zhiwei¹,Hsiao Yi¹,Gao Qi¹

Affiliation:

1. Chemical Development and Drug Product Science and Technology, Bristol-Myers Squibb Company, One Squibb Drive, New Brunswick, New Jersey 08903, United States, and Molecular Sciences and Candidate Optimization, Bristol-Myers Squibb Company, 5 Research Parkway, Wallingford, Connecticut 06492, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ol302262q

Reference21 articles.

1. Calcitonin Gene-Related Peptide Antagonists as Treatments of Migraine and Other Primary Headaches

2. Blockade of CGRP Receptors in the Intracranial Vasculature: A New Target in the Treatment of Headache

3. Neurogenic inflammation in the context of migraine

4. Vasoactive peptide release in the extracerebral circulation of humans during migraine headache

5. The trigeminovascular system and migraine: Studies characterizing cerebrovascular and neuropeptide changes seen in humans and cats

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