4-Hydroxy-5,6-dihydropyrones as Inhibitors of HIV Protease: The Effect of Heterocyclic Substituents at C-6 on Antiviral Potency and Pharmacokinetic Parameters-Reference-Cited by-同舟云学术

4-Hydroxy-5,6-dihydropyrones as Inhibitors of HIV Protease: The Effect of Heterocyclic Substituents at C-6 on Antiviral Potency and Pharmacokinetic Parameters

Published:2001-06-08 Issue:14 Volume:44 Page:2319-2332
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hagen Susan E.¹,Domagala John¹,Gajda Christopher¹,Lovdahl Michael¹,Tait Bradley D.¹,Wise Eric¹,Holler Tod¹,Hupe Donald¹,Nouhan Carolyn¹,Urumov Andrej¹,Zeikus Greg¹,Zeikus Eric¹,Lunney Elizabeth A.¹,Pavlovsky Alexander¹,Gracheck Stephen J.¹,Saunders James¹,VanderRoest Steve¹,Brodfuehrer Joanne¹

Affiliation:

1. Departments of Chemistry, Biochemistry, Biomolecular Structure and Drug Design, Infectious Diseases, and PDM, Pfizer Global Research and Development, 2800 Plymouth Road, Ann Arbor, Michigan 48105

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0003844

Reference29 articles.

1. Antiretroviral Therapy for HIV Infection in 1998

2. Protease Inhibitors in Patients with HIV Disease

3. Drug Interactions of HIV Protease Inhibitors

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