Highly Suppressing Wild-Type HIV-1 and Y181C Mutant HIV-1 Strains by 10-Chloromethyl-11-demethyl-12-oxo-calanolide A with Druggable Profile-Reference-Cited by-同舟云学术

Highly Suppressing Wild-Type HIV-1 and Y181C Mutant HIV-1 Strains by 10-Chloromethyl-11-demethyl-12-oxo-calanolide A with Druggable Profile

Published:2010-01-05 Issue:3 Volume:53 Page:1397-1401
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Xue Hai¹,Lu Xiaofan²,Zheng Purong¹,Liu Li²,Han Chunyan¹,Hu Jinping¹,Liu Zijie¹,Ma Tao¹,Li Yan¹,Wang Lin¹,Chen Zhiwei²,Liu Gang¹

Affiliation:

1. Department of Synthetic Medicinal Chemistry, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 2 Nan Wei Road, Beijing 100050, China

2. AIDS Institute, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Room 45, 5/F Laboratory Block, 21 Sassoon Road, Pokfulam, Hong Kong

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm901653e

Reference22 articles.

1. HIV drug development: the next 25 years

2. Drugs@FDA;http://www.accessdata.fda.gov/scripts/cder/drugsatfda.

3. HIV inhibitory natural products. Part 7. The calanolides, a novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum

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