A Semiquantitative Method for the Determination of Reactive Metabolite Conjugate Levels in Vitro Utilizing Liquid Chromatography−Tandem Mass Spectrometry and Novel Quaternary Ammonium Glutathione Analogues-Reference-Cited by-同舟云学术

A Semiquantitative Method for the Determination of Reactive Metabolite Conjugate Levels in Vitro Utilizing Liquid Chromatography−Tandem Mass Spectrometry and Novel Quaternary Ammonium Glutathione Analogues

Published:2006-02-21 Issue:3 Volume:19 Page:480-490
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Soglia John R.¹,Contillo Leonard G.¹,Kalgutkar Amit S.¹,Zhao Sabrina¹,Hop Cornelis E. C. A.¹,Boyd James G.¹,Cole Mark J.¹

Affiliation:

1. Department of Pharmacokinetics, Dynamics and Metabolism, and Protein Chemistry and Fermentation, Pfizer Central Research, Eastern Point Road, Groton, Connecticut 06340

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx050303c

Reference44 articles.

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3. Elucidating mechanisms of drug-induced toxicity

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