Design and Synthesis of HIV-1 Protease Inhibitors Incorporating Oxazolidinones as P2/P2‘ Ligands in Pseudosymmetric Dipeptide Isosteres-Reference-Cited by-同舟云学术

Design and Synthesis of HIV-1 Protease Inhibitors Incorporating Oxazolidinones as P2/P2‘ Ligands in Pseudosymmetric Dipeptide Isosteres

Published:2007-08-16 Issue:18 Volume:50 Page:4316-4328
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Reddy G. S. Kiran Kumar¹,Ali Akbar¹,Nalam Madhavi N. L.¹,Anjum Saima Ghafoor¹,Cao Hong¹,Nathans Robin S.¹,Schiffer Celia A.¹,Rana Tariq M.¹

Affiliation:

1. Chemical Biology Program and Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm070284z

Reference51 articles.

1. Immunobiology and Pathogenesis of Hepatocellular Injury in Hepatitis B Virus Transgenic Mice

2. L-735,524: The Design of a Potent and Orally Bioavailable HIV Protease Inhibitor

3. ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans.

4. Viracept (Nelfinavir Mesylate, AG1343): A Potent, Orally Bioavailable Inhibitor of HIV-1 Protease

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