Azaindolylsulfonamides, with a More Selective Inhibitory Effect on Histone Deacetylase 6 Activity, Exhibit Antitumor Activity in Colorectal Cancer HCT116 Cells

Author:

Lee Hsueh-Yun1,Tsai An-Chi1,Chen Mei-Chuan2,Shen Po-Jung1,Cheng Yun-Ching3,Kuo Ching-Chuan4,Pan Shiow-Lin5,Liu Yi-Min1,Liu Jin-Fen3,Yeh Teng-Kuang4,Wang Jing-Chi5,Chang Chi-Yen3,Chang Jang-Yang36,Liou Jing-Ping1

Affiliation:

1. School of Pharmacy, College of Pharmacy, Taipei Medical University, 250 Wuxing Street, Taipei 11031, Taiwan

2. Ph.D Program for the Clinical Drug Discovery from Botanical Herbs, College of Pharmacy, Taipei Medical University, Taipei 11031, Taiwan

3. National Institute of Cancer Research, National Health Research Institutes, Tainan 704, Taiwan

4. Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Zhunan Town, Miaoli County, Taiwan

5. The Ph.D Program for Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, 250 Wuxing Street, Taipei 11031, Taiwan

6. Division of Hematology and Oncology, Department of Internal Medicine, National Cheng Kung University Hospital, and College of Medicine, National Cheng Kung University, Tainan, Taiwan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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