Structural Insight into Enantioselective Inversion of an Alcohol Dehydrogenase Reveals a “Polar Gate” in Stereorecognition of Diaryl Ketones-Reference-Cited by-同舟云学术

Structural Insight into Enantioselective Inversion of an Alcohol Dehydrogenase Reveals a “Polar Gate” in Stereorecognition of Diaryl Ketones

Published:2018-09-24 Issue:39 Volume:140 Page:12645-12654
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Zhou Jieyu¹,Wang Yue¹,Xu Guochao¹,Wu Lian²,Han Ruizhi¹,Schwaneberg Ulrich³^ORCID,Rao Yijian¹,Zhao Yi-Lei⁴^ORCID,Zhou Jiahai²,Ni Ye¹^ORCID

Affiliation:

1. Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122 Jiangsu, China

2. State Key Laboratory of Bio-organic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

3. Institute of Biotechnology, RWTH Aachen University, Worringerweg 3, 52074 Aachen, Germany

4. State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China

Funder

Natural Science Foundation of Jiangsu Province

Science and Technology Commission of Shanghai Municipality

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Strategic Priority Research Program (B) of the Chinese Academy of Sciences

Six Talent Peaks Project of Jiangsu Province

Program of Introducing Talents of Discipline to Universities

national first-class discipline program of Light Industry Technolo-gy and Engineering

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.8b08640

Reference83 articles.

1. A randomized, double-blind, crossover comparison among cetirizine, levocetirizine, and ucb 28557 on histamine-induced cutaneous responses in healthy adult volunteers

2. Catalytic asymmetric approaches towards enantiomerically enriched diarylmethanols and diarylmethylamines

3. Copper-Catalyzed Synthesis of Enantioenriched Tetraarylethanes

4. Anti-allergic activity of betotastine besilate (TAU-284), a new anti-allergic drug.

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