Structure-Based Evolution of Low Nanomolar O-GlcNAc Transferase Inhibitors-Reference-Cited by-同舟云学术

Structure-Based Evolution of Low Nanomolar O-GlcNAc Transferase Inhibitors

Published:2018-10-04 Issue:42 Volume:140 Page:13542-13545
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Martin Sara E. S.¹^ORCID,Tan Zhi-Wei¹,Itkonen Harri M.¹,Duveau Damien Y.²,Paulo Joao A.³,Janetzko John¹⁴^ORCID,Boutz Paul L.⁵,Törk Lisa⁴,Moss Frederick A.¹,Thomas Craig J.²,Gygi Steven P.³,Lazarus Michael B.⁶^ORCID,Walker Suzanne¹^ORCID

Affiliation:

1. Department of Microbiology, Harvard Medical School, Boston, Massachusetts 02115, United States

2. Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, Maryland 20892, United States

3. Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, United States

4. Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, United States

5. The David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States

6. Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States

Funder

Agency for Science, Technology and Research

Natural Sciences and Engineering Research Council of Canada

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.8b07328

Reference25 articles.

1. Cross Talk Between O-GlcNAcylation and Phosphorylation: Roles in Signaling, Transcription, and Chronic Disease

2. linking metabolism to epigenetics through O-GlcNAcylation

3. O-GlcNAc signalling: implications for cancer cell biology

4. Protein O-GlcNAcylation: emerging mechanisms and functions

5. Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells

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