A β-Peptide Agonist of the GLP-1 Receptor, a Class B GPCR-Reference-Cited by-同舟云学术

A β-Peptide Agonist of the GLP-1 Receptor, a Class B GPCR

Published:2013-10-02 Issue:20 Volume:15 Page:5318-5321
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Denton Elizabeth V.¹,Craig Cody J.¹,Pongratz Rebecca L.¹,Appelbaum Jacob S.¹,Doerner Amy E.¹,Narayanan Arjun¹,Shulman Gerald I.¹,Cline Gary W.¹,Schepartz Alanna¹

Affiliation:

1. Department of Chemistry, Yale University, New Haven, Connecticut 06511, United States, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06536, United States, Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06520, United States, Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut 06520, United States, Howard Hughes Medical Institute, Yale University School of Medicine,...

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ol402568j

Reference43 articles.

1. Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1.

2. Cloning and functional expression of the human glucagon-like peptide-1 (GLP-1) receptor.

3. The biology of incretin hormones

4. Incretin-based therapies for type 2 diabetes mellitus

5. Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells.

Cited by 38 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Backbone extension acyl rearrangements enable cellular synthesis of proteins with internal β²-peptide linkages;2023-10-03

2. α/Sulfono-γ-AA peptide hybrids agonist of GLP-1R with prolonged action both in vitro and in vivo;Acta Pharmaceutica Sinica B;2023-04

3. Drug Design Methods to Regulate Protein–Protein Interactions;Protein-Protein Interactions;2023

4. Systematic ‘foldamerization’ of peptide inhibiting p53-MDM2/X interactions by the incorporation of trans- or cis-2-aminocyclopentanecarboxylic acid residues;European Journal of Medicinal Chemistry;2020-12

5. Drug discovery approaches targeting the incretin pathway;Bioorganic Chemistry;2020-06