X-ray Absorption Near Edge Structure Spectroscopy to Resolve the in Vivo Chemistry of the Redox-Active Indazolium trans-[Tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019)-Reference-Cited by-同舟云学术

X-ray Absorption Near Edge Structure Spectroscopy to Resolve the in Vivo Chemistry of the Redox-Active Indazolium trans-[Tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019)

Published:2013-01-31 Issue:3 Volume:56 Page:1182-1196
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hummer Alfred A.¹,Heffeter Petra²,Berger Walter²,Filipits Martin²,Batchelor David³,Büchel Gabriel E.⁴,Jakupec Michael A.⁴,Keppler Bernhard K.⁴,Rompel Annette¹

Affiliation:

1. Institut für Biophysikalische Chemie, Universität Wien, Althanstraße 14, 1090 Wien, Austria

2. Institut für Krebsforschung, “Comprehensive Cancer Center” und Forschungsplattform “Translational Cancer Therapy Research”, Medizinische Universität Wien, Borschkegasse 8a, 1090 Wien, Austria

3. Karlsruhe Institut für Technologie (KIT), ANKA, 76344 Eggenstein, Germany

4. Institut für Anorganische Chemie und Forschungsplattform “Translational Cancer Therapy Research”, Universität Wien, Währinger Straße 42, 1090 Wien, Austria

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm301648f

Reference97 articles.

1. Antitumour metal compounds: more than theme and variations

2. Intrinsic and Acquired Forms of Resistance against the Anticancer Ruthenium Compound KP1019 [Indazoliumtrans-[tetrachlorobis(1H-indazole)ruthenate (III)] (FFC14A)

3. Anticancer Activity of Metal Complexes: Involvement of Redox Processes

4. Ruthenium Antimetastatic Agents

5. Interactions of a novel ruthenium-based anticancer drug (KP1019 or FFC14a) with serum proteins ? significance for the patient

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