Click Chemistry Approach to New N-Substituted Aminocyclitols as Potential Pharmacological Chaperones for Gaucher Disease-Reference-Cited by-同舟云学术

Click Chemistry Approach to New N-Substituted Aminocyclitols as Potential Pharmacological Chaperones for Gaucher Disease

Published:2010-06-17 Issue:14 Volume:53 Page:5248-5255
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Díaz Lucía¹,Bujons Jordi²,Casas Josefina³,Llebaria Amadeu³,Delgado Antonio¹³

Affiliation:

1. Facultat de Farmàcia, Unitat de Química Farmacèutica (Unitat Associada al CSIC), Universitat de Barcelona, Avda. Joan XXIII, s/n, 08028 Barcelona, Spain

2. Department de Química Biològica i Modelització Molecular, Institut de Química Avançada de Catalunya (IQAC-CSIC, Spanish National Research Council), Jordi Girona 18-26, 08034 Barcelona, Spain

3. Research Unit on Bioactive Molecules (RUBAM), Departament de Química Biomèdica, Institut de Química Avançada de Catalunya (IQAC-CSIC, Spanish National Research Council), Jordi Girona 18-26, 08034 Barcelona, Spain

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm100198t

Reference45 articles.

1. 1 Gaucher's disease: past, present and future

2. Therapeutic strategies to ameliorate lysosomal storage disorders – a focus on Gaucher disease

3. Pharmacological chaperones: a new twist on receptor folding

4. A contradictory treatment for lysosomal storage disorders: inhibitors enhance mutant enzyme activity

5. Pharmacotherapeutic strategies using small molecules for the treatment of glycolipid lysosomal storage disorders

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